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Trimigno et al

Based on the metabolomics analysis we identified a total of 32 differential metabolites that were significantly reversed by TGP, and discovered 8 key metabolic pathways, including phenylalanine, tyrosine and tryptophan biosynthesis, phenylalanine metabolism, histidine metabolism, starch and sucrose metabolism, arginine and proline metabolism, arginine biosynthesis, glutathione metabolism, and purine metabolism

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Functional targeting of cancer-associated fibroblasts (CAFs) using a combination of DFO and follistatin-like protein 1 (FSTL1) -neutralizing antibody significantly alleviated CAF-induced natural killer cell (NK cell) ferroptosis and boosted the cytotoxicity of NK cells against GC [104]