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doi: 10.1111/1346-8138.12978
1 Smurf1 interacts with PDK1 and activates Akt signaling
This finding suggests that CAR-T in autoimmunity, due to different microenvironments, demonstrates transient persistence and achieves acute B cell aplasia, effectively resetting the immune system (27)
Results can be seen in as little as 2 weeks but the results really begin to reveal themselves at about 6 months
