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These results should therefore be interpreted as exploratory, and future in vitro and in vivo studies will be required to confirm the predicted binding interactions
Also, melanogenic switching was found to be related to tyrosinase activity levels, where high tyrosinase activity produced an excess of dopaquinone resulting in the inactivation of GR and other enzymes essential for pheomelanogenesis [99]
doi: 10.1155/2017/6950642 236
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