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Description
Engineered B
Therapeutic vulnerabilities of cancer stem cells and effects of natural products
GSH is a tripeptide synthesized in all mammalian cells from the amino acid precursors l-glutamate, l-cysteine, and glycine, through the reactions catalyzed by -glutamylcysteine and GSH synthetase
The UPR, which shares molecular machinery with the integrated stress response, halts cap-dependent translation, induces expression of ER chaperone proteins and can lead to death if the stress is not resolved
