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Silencing lipid catabolism is required for fasting induced longevity Next, we investigated the impact of KIN-19 gene silencing on NHR-49 regulation and its subsequent effects on energy homeostasis, animal physiology, and age determination

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In a rat model of diabetes mellitus, meldonium facilitates post-ischemic cardiac recovery by promoting glucose metabolism instead of fatty acids by increasing the activity of pyruvate dehydrogenase and reducing acyl-carnitine concentration [42,43]