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Phosphorylation of parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T alpha-synuclein model of Parkinsons disease

Med 22 , 797 (2024)

Biomolecular condensates: organizers of cellular biochemistry

Among the trials that have been finished is the use of DFO in PD (Phase II), which appeared to reduce nigral iron on MRI but had no effect on the Unified PD Rating Scale (Martin-Bastida et al., 2017)
