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The syringe is inserted into the container and filled to the desired amount for accurate dosing
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However, oral bioavailability is much lower than injectable, meaning the doses are higher (3 mg, 7 mg, and 14 mg tablets compared to the 0.25 to 2.4 mg injectable range)
While there was no indication of a dose-response relationship for effectiveness in Study 1, a dose-response relationship was observed in Study 2, with numerically better responses in the 2 higher dose groups
