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Hormone Replacement Therapy (HRT) and Birth Control Hormone replacement therapy medications and most oral contraceptives contain estrogen without the necessary estrogen and progesterone levels to maintain proper hormone balance, making them causes of estrogen dominance

The authors would also like to thank the Sao Paulo Research Foundation (Fapesp) program for funding a visiting PhD scholarship for J.A.A

4.1 Breast cancer There are numerous lifestyle and biological factors like gene mutations, hormonal changes, familial history, age, reproductive behavior, diet, physical activity, and exposure to mutagens, which might lead to breast tumors (Coughlin, 2019)