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In addition, it has been found that excessive accumulation of iron and zinc ions causes the loss of retinal ganglion cells (RGCs) and that mitochondrial dysfunction caused by excessive accumulation of iron or zinc, including defects in mitochondrial biogenesis and fusion, as well as processes such as fission and an increase in mitochondrial autophagy, constitutes a potential mechanism of glaucoma causation, accelerating the loss of RGCs ( Overall, appropriate intake of minerals is essential for maintaining eye health and preventing glaucoma, but excessive or inappropriate use may be counterproductive

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As shown in Table 4, there was highly significant increase in the of frequency of defecation in KD with L-carnitine supplementation group by 50% in comparison to KD only group that showed decrease in frequency of defecation per week by 33%

The third type of mutation is a splicing mutant