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Thyroid (2019) 29:133643

Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, et al

35.10) consists of two enzymes that catalyze an internal redox reaction in which carbon-1 of MGO is oxidized from an aldehyde to a carboxylic acid group and carbon-2 is reduced from a ketone to a secondary alcohol

This was especially true for men, who showed a more significant reduction in blood pressure levels
