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While NAC is not labeled for intravenous use, NAC can be given intravenously slowly in life-threatening situations at an initial dose of 140 mg/kg, followed by a maintenance rate of 70 mg/kg every six hours for seven treatments [122]

Effector T cells abrogate stroma-mediated chemoresistance in ovarian cancer

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These widespread effects include upregulation of genes involved in matrix synthesis, cell adhesion, growth factor signaling, and tissue remodeling, alongside downregulation of genes associated with inflammation, oxidative stress, and cellular senescence