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Description
An ecdysone-responsive nuclear receptor regulates circadian rhythms in Drosophila
Its current primary use is as a tumor marker in patients with differentiated thyroid cancer to detect recurrent disease and evaluate the efficacy of treatment after thyroidectomy and radioactive iodine ( 131 I)
The acquired resistance of tumor cells to TKIs is partially reversed by inhibiting IGFBP-1 and the combination of antiangiogenic TKIs and IGFBP-1 inhibitors may be a promising therapeutic strategy for HCC (135)
Ho DW, Yang ZF, Yi K, Lam CT, Ng MN, Yu WC, Lau J, Wan T, Wang X, Yan Z, Liu H, Zhang Y, Fan ST
