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Some limitations of antibodies for clinical use are slow diffusion into tumor tissue, limited in vivo stability, and high production costs [7, 11, 12]

While comorbid conditions like long COVID, fibromyalgia (FM), and postural orthostatic tachycardia syndrome (POTS) are common in ME/CFS, the more critical diagnostic complication arises from symptom presentations that resemble pre-malignant states, and undiagnosed rheumatic diseases, neurological diseases and endocrinopathies, increasing the risk of misdiagnosis

Based on the analyses, the proposed methodology resulted in the greatest gains among safety net hospitals and rural hospitals, on average