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Studies comparing 8-OHdG levels in the urine of AD patients and healthy controls have demonstrated positive correlations between 8-OHdG levels and dermatitis scores, indicating disease severity

developed a model of Ox-LDL-induced ferroptosis in HUVECs, showing that CTRP13 intervention increased antioxidant enzyme expression, preventing AS and protecting endothelial cells from ferroptosis ( / mice by reducing mitochondrial damage, boosting glutathione and superoxide dismutase levels, and decreasing LPO and MDA levels

Histological colon sections showed thickened submucosa due to inflammation, cell infiltration, and edema, confirming the UC model

Int J Mol Sci 22:6743