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So when people say does B12 suppress appetite? the honest answer based on trials is: not proven in nondeficient groups

The REDEFINE 1 Phase 3 trial demonstrated 20.4% mean weight loss at 68 weeks in 3,417 participants, and Novo Nordisk has filed an NDA with the FDA
(1985) Effect of cyclosporine administration on renal hemodynamics in conscious rats
