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Description
Screen 101 PochiniL.ScaliseM.GalluccioM.PaniG.SiminovitchK
The clinical appearance is of small blue macules or papules almost always on the palates of children or young adults (Figure 5) [34] and is characterised histopathologically by spindle-shaped melanin-producing naevomelanocytes arranged in fascicles parallel to the overlying epithelium, deep within the lamina propria [11, 13, 34]
PMC 10304509
It plays a significant role in promoting moderate mitochondrial stress, which activates Nrf2, adenosine 5-monophosphate-activated protein kinase (AMPK), and SIRT1 and SIRT3, all of which are involved in anti-inflammatory and antioxidant responses (21, 188)
