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This decrease in 3-HSD and 17-HSD might have occurred due to testicular cell injury, as there was a remarkable rise in oxidative stress in the testicular tissue, or it could be the result of CYP's interference with the transcriptional regulation of the 3-HSD and 17-HSD genes

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Histopathologically, this neoplasm is usually large and asymmetric with a typical trizonal pattern featuring: i) an irregular junctional component with irregular epidermal hyperplasia and areas of prevailing single cell proliferation
