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Increased intestinal permeability, chronic inflammation, oxidative stress, -synuclein aggregation, and neurotransmitter imbalances are some key factors that govern gastrointestinal pathology and PD progression
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PD-1 inhibitors partially recover their interferon-gamma (IFN-) secretion and cytolytic capacity, especially when antigen load is first lowered by siRNAs [12,104,109]

doi: 10.3390/biom12081029 158 PeiJLiuZWangCChuNLiuLTangYet al