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Dopamine in neurotoxicity and neuroprotection: What do D2 receptors have to do with it

NO generated by endothelial nitric oxide synthase (eNOS) not only facilitates vasodilation but also exerts a significant influence on muscle metabolism by enhancing mitochondrial efficiency, facilitating glucose uptake, and promoting the activation of satellite cells (23, 24)

[DOI] [PubMed] [Google Scholar] 44.Peters M.D.J., Godfrey C.M., Khalil H., McInerney P., Parker D., Soares C.B

For patients not responding adequately at 12 weeks on a stable maintenance dose, clinicians should verify proper administration technique, assess adherence patterns, and consider whether further dose escalation is appropriate and tolerable before concluding the medication is ineffective
