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Interestingly, in this case, FAK inhibition only allowed melanoma cells with genetic resistance mechanisms to survive treatment, leading to more predictable resistance mechanisms and the absence of multi-drug resistance 43
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Using a 26 G, 3/8 in intradermal bevel needle, each mouse was administered intraperitoneally with 100 l of the formulated compound suspension at 50 mg/kg, 100 mg/kg and 200 mg/kg
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