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Interestingly, overexpression of the c-KIT tyrosine kinase, a key regulator of melanocytes, has been described in a great number of mucosal melanoma cases (from 39 to 88% depending on the study) and could be a marker or even a target for KIT inhibitors for the treatment of metastatic mucosal melanomas [3, 31]
Reduce the dose by 0.5mg on the next administration
In the case of tumors, alterations in amino acid metabolism can be used not only as clinical indicators of cancer progression but also as therapeutic strategies
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