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FOXO4-DRI competitively disrupts this interaction, potentially restoring apoptotic signaling specifically in senescent cell populations

Nez Selles AJ, Daglia M, Rastrelli L (2016) The potential role of mangiferin in cancer treatment through its immunomodulatory, anti-angiogenic, apoptopic, and gene regulatory effects

The M1 phenotype, stimulated by lipopolysaccharide (LPS) and interferon- (IFN-), was used as a positive control, whereas the M2 phenotype, induced by interleukin-4 (IL-4), functioned as a negative control

& Burckhardt, B
