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Figure 3 Omega-3 fatty acids Among the nutritional intakes, fatty acids (FAs) have a crucial role in determining the composition of lipid-content cell membranes and even cell signaling molecules (124, 125)

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It potently protects sperm mitochondria against electron transport chain-induced ROS through some mechanisms including radical scavenging, iron ions chelating, and increasing expression of mitochondrial antioxidants such as superoxide dismutase (SOD), glutathione (GSH), catalase (CAT), and glutathione peroxidase (GPx), maintains sperm mitochondrial membrane and DNA integrity, and finally modulates the sperm cell apoptotic signaling