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Oral pycnogenol 50 mg twice daily has been suggested to treat melasma, reducing 58% of MASI in 31 Brazilian women after 90 days [87]
doi: 10.1080/15412555.2018.1535581
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Mol Cells 28(4):365368 Yan F, Yang F, Wang R, Yao XJ, Bai L, Zeng X et al (2017) Isoliquiritigenin suppresses human T lymphocyte activation via covalently binding cysteine 46 of IB kinase
