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Other additions to Category 1 include ruxolitinib phosphate, a JAK1and JAK2 inhibitor currently commercially available orally and topically for conditions such as myelofibrosis or atopic dermatitis respectively and dimercaprol,a chelating drug currently commercially-available as an injectable

LL-37 in particular also promotes gingival keratinocyte migration and angiogenesis accelerating the repair of damaged gingival tissue alongside its antimicrobial function

It sits in the membranes of keratinocytes and fibroblasts (the two main cell types responsible for skin structure and barrier function), and it pulls ergothioneine in from both the bloodstream and, when applied topically, from the surface