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19) have the ability to self-assemble into nanoparticles, facilitating effective accumulation in tumor tissues 303,304

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In controlled research environments, it is studied for its involvement in receptor-mediated signaling, peptide-regulated cellular activity, and tissue-focused biochemical models

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73 In mice, systemic cNADK knockout led to either embryonic or preweaning lethality

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In conclusion, a variety of nanoparticles using nanomaterials to deliver TLR agonists have been shown to polarize M2 TAMs to M1 TAMs in TME to exert anti-tumor efficacy

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