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The beneficial effects of mangiferin are primarily due to its antioxidant properties, as evidenced by increased levels of GPx, GST, CAT, and SOD, and its anti-inflammatory effects, indicated by decreased levels of NF-B, TNF-, IL-1, IL-6, and IL-10 [ 67 ]
[DOI] [PubMed] [Google Scholar] 39.Korkushko OV: The results of 30-month use of thymalin and epithalamin in people with the manifestations of an accelerated aging, in International Symposium, Gerontological Aspects of Peptide Regulation of Organism Functions

The absorption of this vitamin is a complex process that involves the stomach, pancreas, small intestine, and liver, so if any one of those organs isnt functioning well, less B12 gets absorbed