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One possible explanation for these apparently conflicting results is that SOD2 protein levels are upregulated through post-translational mechanisms, such as reduced activity of the ubiquitinating enzyme USP36 48 , and that subsequently a feedback adaptation reduces mRNA levels (e.g., via miRNA)

We next explored which type of cell is more sensitive to oxidative stress during the pathogenesis of acute lung injury

Therefore, although many drugs, including matrine [16], curcumin [17] and other natural products derived from traditional Chinese medicines, have shown promising anti-PD potential in vitro, they have failed to exhibit corresponding effects in vivo

Zhao L, Zhang X, Shi Y, Teng T
