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sapiens FLVCR2 with choline bound FLVCR proteins belong to the major facilitator superfamily (MFS), topologically consisting of 12 transmembrane helices that are arranged in an N domain (M1M6) and a C domain (M7M12) around a central twofold symmetry point (Fig 3A) (18, 35)

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They appear suddenly and, contrary to slowly evolving common moles, patients can sometimes date their onset

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