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In addition, many phase 1 clinical trials are testing the efficacy of CAR therapy in solid malignancies by targeting key oncogenic drivers, such as human epidermal growth factor receptor 2 (HER2) and epithelial growth factor receptor (EGFR), which are amplified in many cancers (176)
This clinical trial of teplizumab in patients with new-onset T1D shows that a single 14-day course would attenuate the loss of -cell function
International Labour Organization, 2021)
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