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The dosing landscape for AOD-9604 is genuinely ambiguous because the clinical trials used oral delivery (the compound shows reasonable oral bioavailability, which is unusual for peptides) while most current research applications use subcutaneous injection

All 3 compounds named above affect one particular biomarker of aging, telomere attrition, they have been shown to increase or at least maintain telomere length (Zhou et al 2021

This suggests that ferroptosis, in conjunction with pyroptosis ( via NLRP3), may regulate atherosclerosis progression, offering insights into potential therapeutic targets for CAD ( 4.1.4 Non-coding RNAs as biomarkers for ferroptosis in CAD Beyond protein-based biomarkers, non-coding RNAs have emerged as ferroptosis biomarkers relevant to CAD