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Phase 1: Systematic Screening Start with the Orange Books patent expiration data filtered to a 3-5 year window

If you decide to use that method, remember that your ending inventory might not be representative of other points of the year, especially if you experience seasonal fluctuations

These compounds are typically distributed as research-grade substances, meaning their extended safety data in non-clinical populations remains incomplete

Nevertheless, data generated from multiple groups have demonstrated the presence of senescent cells in postmortem human brain (Figure 1)
