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Acknowledgements The authors wish to thank Mr

doi:10.1073/pnas.0701361104
Similar content being viewed by others Introduction Human skin is an extensive and complex organ responsible for the numerous functions essential for human functioning, including thermoregulation, water management, but also receiving stimuli from the surrounding environment, as well as immune reactions and protection against harmful xenobiotics and external physical factors 1
doi: 10.1016/j.lfs.2009.11.009
