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Kannt A, Rajagopal S, Kadnur SV, et al

Angiogenesis & wound closure (TB-500 / thymosin 4): Thymosin 4 accelerated re-epithelialisation and increased vessel counts in animal wound models [5] , with cell-migration and anti-inflammatory activity described mechanistically [4]

A minimum number of 4 steps (5 proteins) was necessary to reach the end transcription factor in canonical pathway whereas the signal has to pass at least 7 proteins in case of non-canonical pathways such as PCP or Wnt/Ca2+ signaling

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