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TABLE 3 Small-molecule inhibitors targeting the Wnt/-catenin signaling pathway in CRC

In this study, we developed a tyrosine kinase inhibitor 1D228, which exhibited excellent anti-tumor activity by targeting c-Met and TRK

Thus, YAP/TAZ could constitute a crucial molecular mechanism regulating ferroptosis in hepatocellular carcinoma cells while also promoting the emergence of sorafenib resistance [111]

Drug Metab Dispos 43(12):18911904
