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Conversely, oral administration is constrained by enzymatic breakdown, acidic pH, and limited epithelial permeability

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Synthesis and evaluation of asymmetric acyclic nucleoside bisphosphonates as inhibitors of plasmodium falciparum and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferase

Furthermore, the expected shift in population dynamics, with seniors projected to outnumber children under 12 by 2050 underlines their importance in promoting healthy aging and decreasing healthcare burden
