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Epidemiological data indicated that approximately 20% of patients with AP developed severe AP, which was characterized by dysregulated cytokine storms that exacerbate pancreatic damage and precipitate multi-organ failure (e.g., pulmonary insufficiency, intestinal barrier dysfunction) (Iannuzzi et al., 2022), which undoubtedly imposed substantial socioeconomic burdens on patients, families, and healthcare systems

Teresa Chioccarelli, Second University of Naples, Italy Copyright 2014 Guerriero, Trocchia, Abdel-Gawad and Ciarcia

*Correspondence: Yue Gao, [email protected]

That means theyre often issued before a public health threat is confirmed