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Les premires expriences animales menes par Whipple dans les annes 1920, sur les enzymes hpatiques, les maladies du foie et lhmoglobine, dmontrrent que la consommation de foie et de ses extraits amliorait les cas danmie classique, ce qui ouvrit une voie de recherche pour lanmie pernicieuse, encore un grand mystre

Our bodies dont create it, meaning we have to receive it from diet or supplementation

Both involve stimulating fibroblast activity and supporting extracellular matrix production

According to a recent literature review that included seven clinical trials assessing the efficacy of vitamin B12 supplementation in patients with T2D receiving metformin treatment, daily supplementation with methylcobalamin through oral or sublingual administration is preferred over the intramuscular route, considering its effectiveness, cost, and convenience for patients [57]