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Vitamin B12 is a vitamin essential for many bodily functions, including energy production, brain function, and the formation of red blood cells

Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

The vitamin contributes to the survival of nerve cells

A deficiency can also cause a condition called megaloblastic anemia which creates larger, immature, and abnormal red blood cells and leads to impaired DNA synthesis