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AOD-9604 across its full clinical program had no single serious adverse event attributed to the compound

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The suppressed-3-AR phenotype that AOD-9604 appeared to normalize in obese rodents may not carry the same weight in human adipose physiology

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Additionally, engaging in regular physical activity, even moderate-intensity exercise, can increase energy expenditure and contribute to overall calorie balance

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Obesity pharmacotherapy: current perspectives and future directions

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