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This is among the more speculative areas of research

Jan 3, 2026 Understanding what happens when stopping GHK-Cu requires examining the peptide's mechanism of action influencing collagen synthesis, skin regeneration, antioxidant effects, and anti-inflammatory properties to determine whether these changes represent temporary stimulation requiring ongoing supplementation or permanent improvements persisting after treatment cessation

Weber S, Benesic A, Rotter I, Gerbes AL