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The fact that these macrophages can restore motility even in the late stages of the disease model indicates that immune cells could be effective drug carriers across the BBB[188] (Fig

However, in some organisms like fishes, metals can have a long biological half-life that may extend to more than a year in the liver and kidney, reflecting the poor efficiency of excretion pathways (Ruttkay-Nedecky et al., 2013)

Hepatic cancer cell line-based models Although PHHs have become the preferred cell source for liver toxicity assessments, the use of immortalized liver cancer cell lines as alternatives to address the limitations of PHHs has been proposed

Current appraises of therapeutic applications of nanocurcumin: a novel drug delivery approach for biomaterials in dentistry