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Lillo S, Saleh M

Vitamin C enhances glutathione activity, making it an important companion nutrient for stronger benefits

doi: 10.1056/NEJM197111182852108

Both intrinsic factors, properties arising in the malignant cells, such as MYC amplification, PIK3CA , and TP53 mutations, and extrinsic factors, metabolic stresses imposed by the microenvironment, such as hypoxia, oxidative stress, acidosis, contribute to different metabolic programming phenotypes in metastatic breast cancer
