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In Gclm KO mice, we have identified a vicious feed-forward process between OxS and neuro-inflammation occurring early during brain development, which underlies the long-lasting effect on PV neuron/PNN integrity [90]
They assist in keeping adrenal levels in healthy and normal ranges
However, epigenetic alterations are frequently observed in this process and are associated with cisplatin resistance (20, 21)
doi: 10.1016/j.intimp.2019.105832 50 GuiD
