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Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients

Mitochondria play a central role in APAP-induced cell death and injury and therefore greater knowledge about the relationship between mitochondria with other organelles such as lysosomes can result in improved future therapeutic options for APAP-induced liver injury

Panels that pair flux readouts (e.g., DHE2-OH-E for O 2 , compartment-targeted HyPer/roGFP-Orp for H 2 O 2 , peroxiredoxin redox state) with damage footprints (F-isoprostanes, carbonyls/nitrotyrosine, 8-oxoG) and iron/ferroptosis metrics (labile iron pool, oxidized phospholipids, GPX4 context) provide the attribution needed to separate signalling from injury, compare studies and titrate therapy

Biochem Pharmacol 66(8):14991503