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Sudden changes in the diet, especially increased or excessive grain or carbohydrate consumption, can decrease the PH in the rumen and disturb the thiamine production of the microorganisms there
K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts
10.1136/bmj.m2380
