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DTC metal complexes have a relatively long half-life, are widely distributed throughout the body, and penetrate the blood-brain barrier (BBM) (Shirley et al., 2021)

constructed a recombinant virus using A/Wuhan/359/95 (H3N2) and introduced the E276D mutation

Abnormal function of TfR1 can lead to an imbalance of intracellular iron metabolism, increasing iron levels and the risk of ferroptosis

Consequently, MEL, through its interaction with MT1 and MT2 receptors, can regulate cellular processes like oxidative stress, antioxidant enzyme activity, inflammation, and apoptosis, thereby offering protective effects on health