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doi: 10.3349/ymj.2014.55.6.1648
The problems of antigen loss and impaired presentation pose equally fatal challenges
In addition to these defining features, several histologic variants, such as gliosarcomas, giant-cell GBM, small-cell GBM, and epithelioid GBM, present distinct molecular and clinical implications
However, the current understanding remains limited and warrants further mechanistic validation through large-scale cohort studies and experimental investigations
