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Dynamics of CNS barriers: evolution, differentiation, and modulation

Tirz GLP2 (60 mg) utilizes tirzepatide , a synthetic peptide that activates both GLP1 and GIP receptorshormonal pathways central to regulating appetite, improving metabolism, and supporting blood sugar control

o The full pipeline, including semaglutide, cagrilintide, CagriSema, and amycretin, allows Novo Nordisk to serve a broad spectrum of patient needs and preferences, from moderate to very high weight loss (figure 2)

Centrally (para)sagittal venous collateral circulation appears with an occluded superior sagittal sinus (Gojkovic et al., 2021a)