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RussellLBroderickGTaylorRFernandesHHarveyJBarnesZet al
Studies have shown that TSA downregulates extracellular matrix (ECM) gene transcription and collagen expression in dermal fibroblasts by inhibiting the TGF-/Smad and MAPK/ERK signaling pathways, contributing to its antifibrotic effects (60,61)
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
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